This section is intended for patients prescribed Alunbrig. If you are a member of the public click here. If you are a UK healthcare professional click here.

Should I expect any side effects?

Like all medicines, Alunbrig can cause side effects. But not everyone gets them and each person will experience them differently.

Sometimes side effects can make it challenging to stay on treatment, so it's important to talk to your doctor, nurse or pharmacist about them.

You might be worried that your treatment will be stopped if you have side effects. If you do experience side effects during treatment, your doctors or nurse will develop a plan to manage this. This may involve adding other medicines to help with your symptoms, reducing the dose of your treatment or introducing a temporary break in your treatment. In some cases, treatment may need to be stopped and alternative options considered.

Very common side effects (may affect more than 1 in 10 people) include:

  • Feeling sick (nausea)
  • Cough
  • Diarrhoea
  • Headache
  • Tiredness (fatigue)

Please read the Patient Information Leaflet (PIL) for full details on side effects.

What serious side effects do I need to look out for?

There are some things that you need to look out for to help spot certain side effects early. If you notice any of the signs or symptoms listed below, tell your doctor or nurse straight away.


Vision problems

Seeing flashes of light, blurry vision or light hurting your eyes.

Lung problems

New or worsening lung or breathing problems, including chest pain, cough and fever, especially within the first week of taking ALUNBRIG.

Increased blood sugar

The need to urinate more than usual, feeling very thirsty or hungry, weak, tired or confused.

Signs of liver problems

Pain on right side of stomach area, yellowing of your skin or the whites of your eyes, or dark urine.

Slow heartbeat

Chest pain or discomfort, changes in heartbeat, dizziness, light-headedness or fainting.

Signs of inflammation of the pancreas

Upper abdominal pain, including abdominal pain that gets worse with eating or spreads to the back, weight loss, or nausea.

High blood pressure (hypertension)

Headaches, dizziness, blurred vision, chest pain, or shortness of breath.

Signs of muscle damage

Unexplained muscle pain, tenderness, and weakness.

Please refer to your Patient Alert Card for more information.

Your doctor or nurse will provide a Patient Alert Card. Carry your card with you at all times and take it with you to any medical appointments you may have. You should present it to any doctors or nurses treating you, even if they are not your usual treating oncologist or nurse.


Please let your nurse or oncologist know if you lose your patient card, a new one can be provided.

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Patient Alert Card

Carry this card with you at all times and take it with you to any medical appointments you may have. You should present it to any doctors or nurses treating you, even if they are not your usual treating oncologist or lung nurse.

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My Patient Booklet

This guide contains information for people taking Alunbrig for the treatment of ALK-positive advanced non-small cell lung cancer (aNSCLC) after previous crizotinib treatment. It also contains the patient alert card.

Download booklet